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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Jasenthu Kankanamage, Nuwan Dhanushka Miththinda | - |
dc.contributor.author | Gome, James, J. | - |
dc.date.accessioned | 2023-03-17T04:56:57Z | - |
dc.date.available | 2023-03-17T04:56:57Z | - |
dc.date.issued | 2021 | - |
dc.identifier.uri | https://repository.southwesthealthcare.com.au/swhealthcarejspui/handle/1/3422 | - |
dc.description.abstract | Klinefelter syndrome (KS) affects males born with an additional X chromosome giving the genotype 47XXY classically. This syndrome has primary features of infertility and hypogonadism along with other features including a genetically hypercoagulable state. When associated with other risk factors, KS further increases the risk of venous thromboembolism and could result in life-threatening pulmonary embolism (PE). There should be a lower threshold in suspecting PE as a cause of acute respiratory failure in this patient group and thrombolysis should be considered early in normotensive PE with severe hypoxia for best patient outcomes. Furthermore, clinicians should be cautious in managing testosterone therapy in patients with KS and additional thromboembolic risk factors. | - |
dc.relation.isversionof | 20210224 | - |
dc.subject | Human | - |
dc.subject | Hypogonadism | - |
dc.subject | Hypoxia | - |
dc.subject | Klinefelter Syndrome | - |
dc.subject | Male | - |
dc.subject | Pulmonary Embolism | - |
dc.subject | Thrombolytic Therapy | - |
dc.subject | Endocrinology | - |
dc.subject | Pulmonary Embolism | - |
dc.title | Successful thrombolysis of normotensive pulmonary embolism with life-threatening hypoxia in a young man with Klinefelter syndrome | - |
dc.type | Journal Article | - |
dc.identifier.journaltitle | BMJ Case Reports | - |
dc.accession.number | 33627349 | - |
dc.identifier.url | https://casereports.bmj.com/content/14/2/e240118 | - |
dc.description.affiliation | Deakin University - Warrnambool Campus, Warrnambool, Victoria, Australia jkndmiththinda@gmail.com. | - |
dc.description.affiliation | Department of Medicine, South West Healthcare, Warrnambool, Victoria, Australia. | - |
dc.description.affiliation | Deakin University - Warrnambool Campus, Warrnambool, Victoria, Australia. | - |
dc.source.volume | 14 | - |
local.issue.number | 2 | - |
dc.identifier.database | Medline | - |
dc.identifier.notes | eng | - |
dc.identifier.notes | England | - |
dc.identifier.notes | 2021/02/26 | - |
dc.identifier.notes | BMJ Case Rep. 2021 Feb 24;14(2). pii: 14/2/e240118. doi: 10.1136/bcr-2020-240118. | - |
dc.identifier.importdoi | 10.1136/bcr-2020-240118 | - |
dc.identifier.date | Feb 24 | - |
dc.identifier.date | NLM | - |
dc.contributor.swhauthor | Jasenthu Kankanamage, Nuwan Dhanushka Miththinda | - |
dc.contributor.swhauthor | Gome, James, J. | - |
Appears in Collections: | SWH Staff Publications |
Files in This Item:
File | Description | Size | Format | |
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BMJ Case Reports - 2021 - Successful thrombolysis of normotensive pulmonary embolism with life-threatening hypoxia in a young man with Klinefelter syndrome.pdf | 401.32 kB | Adobe PDF | View/Open |
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